Variable input during automatic operation

Is there any practical method to input a variable while a g-code program is running? For example Pause, Request input, Resume, and then use that input.

Currently using 2.8.4 with the Axis interface.

I know multiple ways to change variables when a program is not running, but I have never seen any method for temporarily modifying a running program.

This would allow a single program to process workpieces with different sizes, for example.

I understand this could be dangerous, stupid, or worse. Not planning to be a pioneer.

I searched the forum and the documentation, and I could not find any mention of this topic.

Gene