If you setup ethernet port in the interfaces file,
it will override any network manager settings
(but only after you set the interface down and then up again or reboot)
So you did not successfully change the incorrect 10.10.10.10 host IP address.
I would change it to 10 10.10.100 in the interfaces file, or network manager
and try again (interfaces file changes will not take effect until a reboot or interface
down/up transition)