I had/have very similar issues as you mention earlier today Hakan. The after the pendant disconnected once, it kept doing so every 20 s or so, just like for you. And you see the LIBUSB_ERROR_NO_DEVICE because the dongle has disconnected. However, if you again start LinuxCNC (maybe need to try a couple of times to get the timing right), the pendant will resume working just fine and the disconnects stop for the time being.
As I have said, I believe the reason for the disconnects is that the dongle is unhappy with the current situation and resets itself. And "unhappy with the current situation" is most likely because the host has not been polling its interrupt endpoint for some time (maybe half a second or so).
I attach here a logic analyser screenshot, capture file as well as wireshark capture from a "forced" disconnect event. For this capture, I had the dongle disconnected, LinuxCNC (sim) running a program and in the background waiting for the pendant. I then started all captures, connected the pendant, pressed the Step button (and maybe some others) on the pendant and jogged the wheel. This caused the Usb::setupAsyncTransfer assert failed.
In the screenshot you can see that from approximately 2950 ms (corresponding to wheel jogging), there are no packets until ~3600 ms (except for SOF, which I have turned off on purpose). And at 3750 ms, there is a reset on the USB bus, corresponding to the dongle "disconnecting" and the assert failed. This reset is as far as I'm concerned generated by the dongle itself, because it was unhappy with the conditions.
If I zoom in a little bit on the disconnect/reset event, that becomes more clear. Here I have turned the SOF packets back on, and we see that they are sent every 1 ms as expected. And then suddenly the D+ signal drops to zero, indicating a bus reset (either from the device or the host). And I see no reason why the host should generate a reset in this situation, so I say its generated by the dongle. This is consistent with repeated disconnects every 20 s already discussed.
The .sr file can be opened with PulseView and the .pcapng with Wireshark, in case anybody wants to have a look.
At least for me the pendant is anything but solid. And I do think the dongle firmware is mainly to blame. That being said, it could very well be that different drivers/hardware could mask some of the issues I experience. If only I knew what causes (all) the disconnects, I'm sure we could figure out some ways to fix it.