Can I use these little 3d printer drivers with 7i96?

TL;DR: Can I wire these little TMC2226 (or similar) 3d printer stepper drivers to a 7i96?

Before you laugh I know it seems like a silly matchup. I've been out of the cnc game for a few years now but now I have some projects on mind some I'm trying to plan to reuse some old parts. I'm still fairly out of the loop on the advances made in linuxcnc and hardware since.

I want to build another one of these light weight "3d printed" cncs . By default these machines used arduino/grbl based controllers , but I enjoy linuxcnc so I fully intend on on using linuxcnc instead.

I have a NIB Mesa 7i96 that I never put into production .  I have some raspberry pi 4 Bs laying around from old projects. I would need to find new stepper drivers. These tiny stepper drivers are proven to work fine for these machines. I like the idea of cost and especially space savings with these little chips, and how the original design of the above linked machine integrates their electronics into the gantry. 

So can I just wire these TMC2226s into the 7i96 as a drop in replacement for something  like my old TB6600 s?

I don't quite understand yet if these little chips with all their pins, and uart mode, are a different animal than the old stepper drivers I used before.

PS. I'm excited to find out that there is an official release for the rpi. I've already flashed it and have been poking around in it.

Thank you, sir!

While I've got your attention I have another burning question, though slightly off topic.

As I mentioned I've been out of the loop for several years now. When I was last here plasmac (pre qtplasmac) was in heavy development and rpi4 support was "expiremental" and plasmac a no go.

Is the rpi a viable option now for a plasma table?