Remap M6 in python

Pretty much got everything up and ready on my Biesse conversion but stuck on running the M6 tool change from auto mode in g-code. The M6 works great from the MDI and is really responsive using the self.execute command to execute the M64 and M65 motion output pins, G43 tool offsets etc. but nothing activates when I try and run an M6 in g-code. I've tried adding delays and waits on the interpreter, have messages printing to the log and the code runs but no outputs actually happen. I did see that the entire g-code is read first and it will immediately try the tool change but it doesn't actually happen. I get a successful tool change in my logs but the DRO and tool info don't update and none of the outputs actually fire to raise and lower solenoids for that bit. It seems like this is something really simple but struggling to find it! Any suggestions?