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All PC's in probably last 10 or more years like to have 2 memory modules as they can all do dual channel communication.
Some Xeon's and AMD can evem do 4 channels.
And yes, more memory improves latency, so 8GB should be minimum and there is no reason to have over 16GB for Linux and LinuxCNC if used for machine control only.
When possible, always choose 2x4gb or 2x8gb.

Did you change the the dtb in /boot/armbianEnv.txt
fdtfile=rockchip/rk3399-orangepi-4-lts.dtb
-> fdtfile=rockchip/rk3399-orangepi-4.dtb
+ extraargs=isolcpus=5 or 2-5

And what result do you get?

To prevent the rt kernel from getting overwritten you could hold the package with: sudo apt-mark hold packagename

First make sure both motors on the X axis are turning in proper directions.
Make a new config with no tandem and set the X axis to both outputs, then do very small jogs to check.

Right now you can have a tool touch off button for each axis but the line edit to enter the touch off value there is only one.

What is your use case for needing multiple line edits?

Can you post a screen shot of your gui?

JT